963 COMPLETE TUMOR ABLATION WITH IODINE 131 RADIOLABELED MONOCLONAL ANTIBODY (Mab) AGAINST HUMAN NEUROBLASTOMA (NB) XENOGRAFTED IN NUDE MICE
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منابع مشابه
Radiolocalization of xenografted human lung cancer with monoclonal antibody 8 in nude mice.
A monoclonal antibody (MAb) 8 [immunoglobulin G3 (IgG3)], directed against a Mr 48,000 human lung cancer-associated antigen, was radiolabeled with either 125I or 131I, and its biodistribution was studied in nude mice bearing human lung cancer (TKB-2) over a 7-day period. 125I-labeled MAb 8 increased its binding to the tumor during the period, while the binding of 125I-labeled control IgG3 decli...
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A monoclonal antibody (MAb) 8 (¡mmunoglobulin G3 (IgG3)|, directed against a M, 48,000 human lung cancer-associated antigen, was radiolabeled with either 12!I or '"I, and its biodistribution was studied in nude mice bearing human lung cancer (TKB-2) over a 7-day period. I25l-labeled MAb 8 increased its binding to the tumor during the period, while the binding of 125I-labeled control IgG3 decli...
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UNLABELLED The aim of this study was to determine if pulsed high-intensity focused ultrasound (HIFU) exposures could enhance tumor uptake of (111)In-MX-B3, a murine IgG1kappa monoclonal antibody directed against the Le(y) antigen. METHODS MX-B3 was labeled with (111)In, purified, and confirmed for its binding to the antigen-positive A431 cell line. Groups of nude mice were inoculated subcutan...
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Anti-ras p21 monoclonal antibody (RASK-3) was used for immunoscintigraphy of human cancer cell lines in nude mice. Iodine-125-labeled RASK-3 was injected into nude mice with either human colon cancers (FCC-1 or BM-314) or lung cancer (KNS-62). Clear images were obtained in all three cancers 7 days after the injection of antibody. No localization of 125I-labeled control monoclonal antibody was o...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198504000-00993